104. Eunju Jang, Yeji Lee, Eunju Ko, Michaela Jeong, Jun Chang Hyukjin Lee. Development of lipid nanoparticle formulation for intramuscular administration of mRNA vaccine against respiratory syncytial virus. Journal of Pharmaceutical Investigation. 2025, doi: 10.1007/s40005-024-00719-1

103. Hee Jin, So-Yeon Park, Ji Eun Lee, Hangyeol Park, Michaela Jeong, Hyukjin Lee, Jaeho Cho, Yun-Sil Lee. GTSE1-driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition. Molecular Therapy. 2024, doi: 10.1016/j.ymthe.2024.09.029

102. Seongryong Kim, Ji Hyang Jeon, Myeonghwan Kim, Yeji Lee, Yun-Ho Hwang, Myungsun Park, C. Han Li, Taeyoung Lee, Jung-Ah Lee, You-Me Kim, Dokeun Kim, Hyukjin Lee., You-Jin Kim, V. Narry Kim, Jong-Eun Park & Jinah Yeo. Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site. Nature Communications. 2024, doi: 10.1038/s41467-024-51411-9

101. Michaela Jeong, Sumin Shin, Gyeongseok Lee, Yeji Lee, Seo Bhin Park, Jisoo Kang, Young-Sun Lee, Wonhyo Seo, Hyukjin Lee. Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis. Journal of Controlled Release. 2024, doi: 10.1016/j.jconrel.2024.08.012

100. Sangho Yeo, Hyeondo Lee, Junhyuk Lee, Hyukjin Lee, Hyejung Mok. Optimization of polyethylene glycol shielding and mannose density on the lipid nanoparticles for efficient delivery to macrophages and spleens. International Journal of Pharmaceutics. 2024, doi: 10.1016/j.ijpharm.2024.124540

99. Yeji Lee, Michaela Jeong, Gyeongseok Lee, Jeongeun Park, Hyein Jung, Seongeun Im, Hyukjin Lee. Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics. Biomaterials Research. 2024, doi: 10.34133/bmr.0017

98. H Kim, S Kim, D Lee, D Lee, J Yoon, H Lee. Oligonucleotide therapeutics and their chemical modification strategies for clinical applications Journal of Pharmaceutical Investigation. 2024, doi: 10.1007/s40005-024-00669-8

97. Jeong Pil Han, Yeji Lee, Jeong Hyeon Lee, Hye Yoon Chung, Geon Seong Lee, Yu Ri Nam, Myeongjin Choi, Kyoung-Sik Moon, Haeshin Lee, Hyukjin Lee, Su Cheong Yeom. In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice. Molecular Therapy Nucleic Acids. 2023, 34, 102050, doi: 10.1016/j.omtn.2023.102050

96. Yeji Lee, Michaela Jeong, Jeongeun Park, Hyein Jung, Hyukjin Lee. Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics. Experimental & Molecular Medicine. 2023, 55, 2085-2096, doi: 10.1038/s12276-023-01086-x

95. Jisu Kim, Ying Zhu, Sunhui Chen, Dongdong Wang, Shuya Zhang, Jiaxuan Xia, Shiyi Li, Qiujun Qiu, Hyukjin Lee, Jianxin Wang. Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood-brain-barrier penetration and tumor microenvironment modulation. Journal of Nanobiotechnology. 2023, 21(1):253. doi: 10.1186/s12951-023-02006-x

94. In Gyu Kim, Won Ho Jung, Gayeon You, Hyukjin Lee, Yoo Jin Shin, Sun Woo Lim, Byung Ha Chung, Hyejung Mok. Efficient Delivery of Globotriaosylceramide Synthase siRNA using Polyhistidine-Incorporated Lipid Nanoparticles. Macromolecular Bioscience. 2023, 23(4):e2200423. doi: 10.1002/mabi.202200423

93. Michaela Jeong, Yeji Lee, Jeongeun Park, Hyein Jung, Hyukjin Lee. Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications. Advanced Drug Delivery Reviews. 2023, 200;114990. doi: 10.1016/j.addr.2023.114990

92. Minjeong Kim, Michaela Jeong, Gyeongseok Lee, Yeji Lee, Jeongeun Park, Hyein Jung, Seongeun Im, Joo-Sung Yang, Kyungjin Kim, Hyukjin Lee. Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety. Bioeng Transl Med. 2023, 8(6);e10556. doi: 0.1002/btm2.10556

91. Lee JH, Han JP, Song DW, Lee GS, Choi BS, Kim M, Lee Y, Kim S, Lee H, Yeom SC. In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector. Mol Ther Nucleic Acids. 2023 Mar 21;32:161-172. doi: 10.1016/j.omtn.2023.03.008.

90. Hee Jin, Michaela Jeong, Gyeongseok Lee, Minjeong Kim, Youngjo Yoo, Hyun Jin Kim, Jaeho Cho, Yun-Sil Lee, Hyukjin Lee. Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs. Adv. Funct. Mater. 2022, 23, 7, 2209432 doi: 10.1002/adfm.202209432

89. Hyunsook Kim, Bora Jang, Dayoung Lee, S. Chul Kwon, and Hyukjin Lee. Artificial pri-miRNAs as a platform for simultaneous delivery of siRNA and antisense oligonucleotide. Journal of Controlled Release, Volume 349, 2022, Pages 983-991. doi: 10.1016/j.jconrel.2022.07.043

88. Suji Kwon, Minseon Kwon, Seongeun Im, Kyuri Lee, Hyukjin Lee. mRNA vaccines: the most recent clinical applications of synthetic mRNA. Archives of Pharmacal Research 45, 245–262 (2022) doi: 10.1007/s12272-022-01381-7

87. Swarup Kumar Maji, Subin Yu, Eunshil Choi, Ju Won Lim, Dohyub Jang, Ga-young Kim, Sehoon Kim, Hyukjin Lee, and Dong Ha Kim. Anisotropic Plasmonic Gold Nanorod–Indocyanine Green@Reduced Graphene Oxide–Doxorubicin Nanohybrids for Image-Guided Enhanced Tumor Theranostics. ACS Omega, 2022,7,15186−15199. doi: 10.1021/acsomega.2c01306

86. Han JP, Kim M, Choi BS, Lee JH, Lee GS, Jeong M, Lee Y, Kim EA, Oh HK, Go N, Lee H, Lee KJ, Kim UG, Lee JY, Kim S, Chang J, Lee H, Song DW, Yeom SC. In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy. Sci Adv. 2022 Jan 21;8(3):eabj6901. doi: 10.1126/sciadv.abj6901

85. Chan-Jin Kim, Ga-Hyun Kim, Eun Hye Jeong, Hyukjin Lee and So-Jung Park. The core composition of DNA block copolymer micelles dictates DNA hybridization properties, nuclease stabilities, and cellular uptake efficiencies. Nanoscale. 2021, 13, 13758-13763. doi: 10.1039/D1NR00756D

84. Subin Yu, Dohyub Jang, Hong Yuan, Wen-Tse Huang, Minju Kim, Filipe Marques Mota, Ru-Shi Liu, Hyukjin Lee, Sehoon Kim, and Dong Ha Kim. Plasmon-Triggered Upconversion Emissions and Hot Carrier Injection for Combinatorial Photothermal and Photodynamic Cancer Therapy. ACS Applied Materials & Interfaces. 2021 13(49), 58422-58433. doi: 10.1021/acsami.1c21949

83. Bora Jang, Hyejin Jang, Hyunsook Kim, Minjeong Kim, Michaela Jeong, Gyeong Seok Lee, Kyuri Lee, Hyukjin Lee, Protein-RNA interaction guided chemical modification of Dicer substrate RNA nanostructures for superior in vivo gene silencing, Journal of Controlled Release, Volume 343, 2022, Pages 57-65. doi: 10.1016/j.jconrel.2021.11.009

82. Kim M, Jeong M, Hur S, Cho Y, Park J, Jung H, Seo Y, Woo HA, Nam KT, Lee K, Lee H. Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver. Sci Adv. 2021 Feb 26;7(9):eabf4398. doi: 10.1126/sciadv.abf4398

81. Kim, J.; Park, B.; Shin, D.H.; Yoo, J.M.; Lee, H.; Hong, B.H. Photocatalytic Degradation of Phenol Using Chemical Vapor Desposition Graphene Column. Catalysts 2020, 10, 1251. https://doi.org/10.3390/catal10111251

80. H.-J. Park, E.-K. Bang, J. J. Hong, S.-M. Lee, H. L. Ko, H. W. Kwak, H. Park, K. W. Kang, R.-H. Kim, S. R. Ryu, G. Kim, H. Oh, H.-J. Kim, K. Lee, M. Kim, S. Y. Kim, J.-O. Kim, K. El-Baz, H. Lee, M. Song, D. G. Jeong, G. Keum, J.-H. Nam, Nanoformulated Single-Stranded RNA-Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen-Presenting Cells, Angew. Chem. Int. Ed. 2020, 59, 11540. https://doi.org/10.1002/anie.202002979

79. Inah Hwang, Md Jamal Uddin, Eun Seon Pak, Hyeji Kang, Eun-Jung Jin, Suin Jo, Dongmin Kang, Hyukjin Lee, Hunjoo Ha, The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress, Free Radical Biology and Medicine, Volume 148, 2020, Pages 22-32, ISSN 0891-5849, https://doi.org/10.1016/j.freeradbiomed.2019.12.025.

78. Kyuri Lee, Tae-Shin Kim, Yunmi Seo, Soo Young Kim, Hyukjin Lee, Combined hybrid structure of siRNA tailed IVT mRNA (ChriST mRNA) for enhancing DC maturation and subsequent anticancer T cell immunity, Journal of Controlled Release, Volume 327, 2020, Pages 225-234, ISSN 0168-3659, https://doi.org/10.1016/j.jconrel.2020.08.009.

77. Jooyeong Kim, Jin Kyung Ahn, Ji Su Kim, Bo Ram Choi, Juyeon Cho, Hyukjin Lee, Highly selective detection of single nucleotide polymorphism (SNP) using a dumbbell DNA probe with a gap-filling approach, Journal of Industrial and Engineering Chemistry, Volume 88, 2020, Pages 78-83, ISSN 1226-086X, https://doi.org/10.1016/j.jiec.2020.03.028.

76. Lee K, Kim SY, Seo Y, Kim MH, Chang J, Lee H. Adjuvant incorporated lipid nanoparticles for enhanced mRNA-mediated cancer immunotherapy. Biomater Sci. 2020 Feb 21;8(4):1101-1105. doi:10.1039/c9bm01564g

75. Cho KA, Lee HJ, Jeong H, Kim M, Jung SY, Park HS, Ryu KH, Lee SJ, Jeong B, Lee H, Kim HS. Tonsil-derived stem cells as a new source of adult stem cells. World J Stem Cells. 2019 Aug 26;11(8):506-518. doi: 10.4252/wjsc.v11.i8.506

74. S. Lee, Y. M. Lee, H.-J. Lee, H. Jeon, H. Lee, D. Shin, S. Kim, Membrane Fusion through the Generation of Triazole Ceramide via Click Chemistry at the Membrane Surface, Asian J. Org. Chem. 2019, 8, 1713. https://doi.org/10.1002/ajoc.201900342

73. Kyuri Lee, Soo Young Kim, Yunmi Seo, Hyokyung Kwon, Young Jik Kwon, Hyukjin Lee, Multicistronic IVT mRNA for simultaneous expression of multiple fluorescent proteins, Journal of Industrial and Engineering Chemistry, Volume 80, 2019, Pages 770-777, ISSN 1226-086X, https://doi.org/10.1016/j.jiec.2019.06.042.

72. Jeonghun Nam, Woong Sik Jang, Jisu Kim, Hyukjin Lee, Chae Seung Lim, Lamb wave-based molecular diagnosis using DNA hydrogel formation by rolling circle amplification (RCA) process, Biosensors and Bioelectronics, Volume 142, 2019, 111496, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2019.111496.

71. Swarup Kumar Maji, Subin Yu, Kyungwha Chung, Madeshwaran Sekkarapatti Ramasamy, Ju Won Lim, Jianfang Wang, Hyukjin Lee, and Dong Ha Kim ACS Applied Materials & Interfaces 2018 10 (49), 42068-42076, DOI: 10.1021/acsami.8b15443

70. Kim C.J., Jeong E.H., Lee, H., Park S.J., “A dynamic DNA nanostructure with switchable and size-selective molecular recognition properties”, Nanoscale, 11(5), 2501-2509, 2019. https://doi.org/10.1039/c8nr09341e

69. Choi B.R., Cho J., Kim, J., Kim J.S., Kim K., Lee, H., “Capillary Tube Based Molecular Diagnostic Test for Naked Eye Detection of Antibiotic Resistant Bacteria”, Advanced Materials Technologies, 4(1), 1800375, 2019. https://doi.org/10.1002/admt.201800375

68. Maji S.K., Yu S., Chung K., Ramasamy M., Lim J.W., Wang J., Lee H., Kim D.H., “Synergistic Nanozymetic Activity of Hybrid Gold Bipyramid–Molybdenum Disulfide Core@ Shell Nanostructures for Two-Photon Imaging and Anticancer Therapy”, ACS applied materials & interfaces, 10(49), 42068-42076, 2018. https://doi.org/10.1021/acsami.8b15443

67. Lee K., Kim M., Seo Y., Lee H., “Development of mRNA vaccines and their prophylactic and therapeutic applications”, Nano Research, 11(10), 5173-5192, 2018. https://doi.org/10.1007/s12274-018-2095-8

66. Chae A., Choi B.R., Choi Y., Jo S., Kang E.B., Lee H., Park S.Y., In I., “Mechanochemical synthesis of fluorescent carbon dots from cellulose powders” Nanotechnology, 29(16), 165604., 2018. https://doi.org/10.1088/1361-6528/aaad49

65. Yoo J.M., Park B., Kim S.J., Choi Y.S., Park S., Jeong E.H., Lee H., Hong B.H., “Catalytic degradation of phenols by recyclable CVD graphene films”, Nanoscale, 10(13), 5840-5844, 2018. https://doi.org/10.1039/c8nr00045j

64. Kyung H., Kim H., Lee H., Lee S.J., “Enhanced intracellular delivery of macromolecules by melittin derivatives mediated cellular uptake”, Journal of industrial and engineering chemistry, 58, 290-295, 2018. https://doi.org/10.1016/j.jiec.2017.09.039

63. Ye J., Pei X., Cui H., Yu Z., Lee H., Wang J., Wang X., Sun L., He H., Yang V.C. (2018). “Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate”, Journal of industrial and engineering chemistry, 63, 103-111, 2018. https://doi.org/10.1016/j.jiec.2018.02.005

62. Kwon H., Kim M., Seo Y., Moon Y.S., Lee H.J., Lee K., Lee H., “Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine”, Biomaterials, 156, 172-193, 2018. https://doi.org/10.1016/j.biomaterials.2017.11.034

61. Sun L., Xie S., Ji X., Zhang J., Wang D., Lee S.J., Lee H., He H., Yang V.C. “MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging”, Biomaterials science, 6(10), 2619-2626., 2018 https://doi.org/10.1039/x0xx00000x

60. Lee K., Jang B., Lee Y.R., Suh E.Y., Yoo J.S., Lee M.J., Lee J.Y., Lee H., “The cutting-edge technologies of siRNA delivery and their application in clinical trials”, Archives of pharmacal research, 41(9), 867-874, 2018. https://doi.org/10.1007/s12272-018-1069-4

59. Jang B., Kim, B., Kim H., Kwon H., Kim M., Seo Y., Colas M,, Jeong H., Jeong E.H., Lee K., Lee H., “Enzymatic synthesis of self-assembled dicer substrate RNA nanostructures for programmable gene silencing”, Nano letters, 18(7), 4279-4284, 2018. https://doi.org/10.1021/acs.nanolett.8b01267

58. Park M. J., Choi H. H., Park B., Lee J. Y., Lee C. H., Choi Y. S., Kim Y., Lee H., Hong, B. H., “Enhanced Chemical Reactivity of Graphene by Fermi Level Modulation”, Chemistry of Materials, 30(16), 5602-5609, 2018. https://doi.org/10.1021/acs.chemmater.8b01614

57. Kwon H.K.,. Kim M.J, Seo Y.M., Moon Y.S., Lee H.J., Lee K.R.**, Lee H.*, “Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine”, Biomaterials, 156, 172-193, 2018. https://doi.org/10.1016/j.biomaterials.2017.11.034

56. Kyung H.W., Kim H..J., Lee H.*, Lee S.J., “Enhanced intracellular delivery of macromolecules by melittin derivatives mediated cellular uptake”, Journal of Industrial and Engineering Chemistry, 58, 290-295, 2018. https://doi.org/10.1016/j.jiec.2017.09.039

55. Yhee J.Y., Jeon S.M., Yoon H.Y., Shim M.K., Ko H.W., Min J.W., Na J.H., Chang H.Y., Han H.K., Kim J.H., Suh M.N., Lee H., Park J.H, Kim K.M., Kwon I.C., “Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles”, Journal of Controlled Release, 267, 223-231, 2017. https://doi.org/10.1016/j.jconrel.2017.09.015

54. Jeong E.H., Jeong H.S., Jang B.R., Kim B.Y., Kim M.J., Kwon H.K., Lee K.R.*, Lee H*, “Aptamer-incorporated DNA Holliday junction for the targeted delivery of siRNA”, Journal of Industrial and Engineering Chemistry, 56, 55-61, 2017. https://doi.org/10.1016/j.jiec.2017.07.025

53. Kang J.H., Kim K.R., Lee H., Ahn D.R., Ko Y.T.,*, “In vitro and in vivo behavior of DNA tetrahedrons as tumor-targetingnanocarriers for doxorubicin delivery”, Colloids and Surfaces B: Biointerfaces, 157, 424–431, 2017. http://dx.doi.org/10.1016/j.colsurfb.2017.06.014

52. Lee S.M., Han H.K., Koo H.B., Na J.H., Yoon H.Y., Lee K.E., Lee H., Kim H.C., Kwon I.C., Kim K.M.*, “Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensityfocused ultrasound”, Journal of Controlled Release, 263, 68-78, 2017. https://doi.org/10.1016/j.jconrel.2017.02.035

51. Yoon H.Y., Shin M.L., Shim M.K., Lee S.M., Na J.H., Koo H.B., Lee H., Kim J.H., Lee K.Y., Kim K.M., Kwon I.C., “Artificial Chemical Reporter Targeting Strategy Using Bioorthogonal Click Reaction for Improving Active-Targeting Efficiency of Tumor”, Mol. Pharmaceutics, 14, 2017. DOI: 10.1021/acs.molpharmaceut.6b01083

50. Jung I.Y., Kim J.S., Choi B.R., Lee K.R,* Lee H.*, “Hydrogel Based Biosensors for In Vitro Diagnostics of Biochemicals, Proteins, and Genes”, Adv. Healthcare Mater, 6, 2017. http://dx.doi.org/10.1002/adhm.201601475

49. Kim K.R., Kim H.Y., Lee Y.D., Ha J.S., Kang J.H., Jeong H.S., Bang D.H., Ko Y.T., Kim S.H., Lee H., Ahn D.R.* “Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs”, Journal of Controlled Release, 243, 121-131, 2016. https://doi.org/10.1016/j.jconrel.2016.10.015

48. Lee S.Y., Lee S.M., Lee J.W., Yhee J.Y., Yoon H.I., Park S.J, Koo H.B., Moon S.H., Lee H.*, Cho Y.W., Kang S.W., Lee S.Y., Kim K.M.*, “Non-invasive stem cell tracking in hindlimb ischemia animal model using bio-orthogonal copper-free click chemistry”, Biochemical and Biophysical Research Communications, 479, 779-786, 2016. https://doi.org/10.1016/j.bbrc.2016.09.132

47. Song I.T., Lee M.H., Lee H., Han J.N.. Jang J.H., Lee M.S., Koh G.Y, Lee H.S., “PEGylation and HAylation via catechol: a-Amine-specific reaction at N-terminus of peptides and proteins”, Acta Biomaterialia, 43, 50-60, 2016. https://doi.org/10.1016/j.actbio.2016.07.018

46. Yoon H.I., Yhee J.Y., Na J.H., Lee S.M., Lee H., Kang S.W., Chang H.Y., Ryu J.H., Lee S.K, Kwon I.C., Cho Y.W., Kim K.M., “Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo”, Bioconjugate Chem, 27, 927−936, 2016. http://dx.doi.org/10.1021/acs.bioconjchem.6b00010

45. Kim J.E., Choi J.H., Colas M., Kim D.H.* and Lee H.* “Gold-based hybrid nanomaterials for biosensing and molecular diagnostic applications”, Biosens Bioelectron, 80, 543-559, 2016. doi:10.1016/j.bios.2016.02.015

44. Jung I.Y., You J.B., Choi B.R., Kim J.S., Lee H.K., Jang B., Jeong H.S., Lee K., Im S.G.* and Lee H.* “A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus”, Adv Healthc Mater, 2016 http://dx.doi.org/10.1002/adhm.201600334

43. Jung I.Y., Lee E.H., Suh A.Y., Lee S.J. and Lee H.* “Oligonucleotide-based biosensors for in vitro diagnostics and environmental hazard detection”, Anal Bioanal Chem, 408, 2383-2406, 2016 http://dx.doi.org/10.1007/s00216-015-9212-2

42. Jeong H., Lee E.S., Jung G., Park J., Jeong B., Ryu K.H., Hwang N.S.* and Lee H.* “Bioreducible-Cationic Poly(amido amine)s for Enhanced Gene Delivery and Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells”, J Biomed Nanotechnol, 12, 1023-1034, 2016 http://dx.doi.org/10.1166/jbn.2016.2223

41. Jang B., Kwon H., Katila P., Lee S.J. and Lee H.* “Dual delivery of biological therapeutics for multimodal and synergistic cancer therapies”, Adv Drug Deliv Rev, 98, 113-133, 2016 doi:10.1016/j.addr.2015.10.023

40. Yhee J.Y., Son S., Lee H. and Kim K.* “Nanoparticle-Based Combination Therapy for Cancer Treatment”, Curr Pharm Des, 21, 3158-3166, 2015 doi:10.1016/j.bcp.2012.01.008

39. Yhee J.Y., Kim Y.J., Ryu J.H., Yoon H.Y., Chang H., Park J.H., Lee H., Jang H.S., Jeong U., Kim K.* and Kang S.W.* “Cathepsin B Imaging to Predict Quality of Engineered Cartilage”, Macromol Biosci, 15, 1224-1232, 2015 http://dx.doi.org/10.1002/mabi.201500215

38. Ro H., Park J., Yang K., Kim J., Yim H.G., Jung G., Lee H., Cho S.W. and Hwang N.S.* “Osteogenic priming of mesenchymal stem cells by chondrocyte-conditioned factors and mineralized matrix”, Cell Tissue Res, 362, 115-126, 2015 http://dx.doi.org/10.1007/s00441-015-2195-7

37. Lee S.J., Yook S., Yhee J.Y., Yoon H.Y., Kim M.G., Ku S.H., Kim S.H., Park J.H., Jeong J.H., Kwon I.C., Lee S, Lee Hand Kim K.* “Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo”, J Control Release, 220, 631-641, 2015 http://dx.doi.org/10.1016/j.jconrel.2015.08.032

36. Jeong E.H., Kim H., Jang B., Cho H., Ryu J., Kim B., Park Y., Kim J., Lee J.B.* and Lee H.* “Technological development of structural DNA/RNA-based RNAi systems and their applications”, Adv Drug Deliv Rev., 2015 doi:10.1016/j.addr.2015.10.008

35. Lee H.Y., Jeong H., Jung I.Y., Jang B., Seo Y.C., Lee H., and Lee H*, “DhiTACT: DNA hydrogel formation by isothermal amplification of complementary target in fluidic channels”, Adv. Mater. 27, 3466, 2015 http://dx.doi.org/10.1002/adma.201500414

34. Hong C.A., Eltoukhy A.A., Lee H., Langer R., Anderson D.G., and Nam Y.S. “Dendrimeric siRNA for Efficient Gene Silencing”, Angew Chem Int Ed,54, 6740, 2015 http://dx.doi.org/10.1002/anie.201412493

33. Kim H.J., Chung K., Lee S.J., Kim D.H., and Lee H.*, “Near-infrared light-responsive nanomaterials for cancer theranostics”, WIREs Nanomed Nanotechnol, DOI: 10.1002/wnan.1347, 2015 http://dx.doi.org/10.1002/wnan.1347

32. Maeng J., Kim M., Lee H., and Lee K., “Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells”, Int. J Mol Sci. 16, 7565-7576, 2015 http://dx.doi.org/10.3390/ijms16047565

31. Park M., Kim Y.H., Woo S.Y., Lee H.J., Yu Y., Kim H.S., Park Y.S., Jo I., Park J.W., Jung S.C., >Lee H., Jeong B., and Ryu K.H., “Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation”, Sci Rep. 5, 8616, 2015 http://dx.doi.org/10.1038/srep08616

30. Kim J.T., Chung H.J., Seo J.Y., Yang Y.I., Choi M.Y., Kim H.I., Yang T.H., Lee W.J., Youn Y.C., Kim H.J., Kim Y.M., Lee H., Jang Y.S. and , Lee S.J., “A fibrin-supported myocardial organ culture for isolation of cardiac stem cells via the recapitulation of cardiac homeostasis”, Biomaterials 48, 66-83, 2015 doi:10.1016/j.biomaterials.2015.01.041

29. Hong J., Lee E.A., Jung J., Jeong H., Lee H.*, and Hwang NS, “Induced myogenic commitment of human chondrocytes via non-viral delivery of minicircle DNA”, J. Controlled Release 200, 212-221, 2015 doi:10.1016/j.jconrel.2014.12.031

28. Jeong E.H., Ryu J.H., Jeong H., Jang B., Lee H., Hong S., Lee H., and Lee H.*, “Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells”, Chem. Commun. 50,13388-13390, 2014 http://dx.doi.org/10.1039/C4CC07155G

27. Hong C.A., Jang B., Jeong E.H., Jeong H., and Lee H.* “Self-assembled DNA nanostructures prepared by rolling circle amplification for the delivery of siRNA conjugates”, Chem. Commun. 50, 13049-13051, 2014 http://dx.doi.org/10.1039/C4CC03834G

26. Lee S.Y., Kim S.H., Kim S.M., Lee H., Lee G., and Park S.Y. “Tunable and selective detection of cancer cells using a betainized zwitterionic polymer with BODIPY and graphene oxide”, New J. Chem. DOI: 10.1039/c3nj01641b, 2014 http://dx.doi.org/10.1039/C3NJ01641B

25. Hong S., Yeom J., Song I.T., Kang S.M., Lee H., and Lee H.* “Pyrogallol 2-Aminoethane: A Plant Flavonoid-Inspired Molecule for Material-Independent Surface Chemistry”, Adv. Mater.Interfaces DOI: 10.1002/admi.201400113, 2014 http://dx.doi.org/10.1002/admi.201400113

24. Park M.H., Yu Y., Moon H.J., Ko D.Y., Kim H.S., Lee H., Ryu K.H, and Jeong B. “3D Culture of Tonsil-Derived Mesenchymal Stem Cells in Poly(ethylene glycol)-Poly(L-alanine-co-L-phenyl alanine) Thermogel”, Adv. Healthcare Mater. 11, 1782-1791, 2014 http://dx.doi.org/10.1002/adhm.201400140

23. Hong S., Lee H., and Lee H. “Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions”, Beilstein J. Nanotechnol. 5, 887-894, 2014 http://dx.doi.org/10.3762/bjnano.5.101

22. Lee S.Y., Lee H., In I., and Park S.Y. “pH/redox/photo responsive polymeric micelle via boronate ester and disulfide bonds with spiropyran-based photochromic polymer for cell imaging and anticancer drug delivery”, European Polymer Journal 57, 1-10, 2014 doi:10.1016/j.eurpolymj.2014.04.020

21. Lee H., and Kim Y. “Nanobiomaterials for pharmaceutical and medical applications”, Archives of Pharmacal Research 37, 1-3, 2014

20. Jeong EH., Jung JY., Hong C.A., Lee H.* “Gold Nanoparticle (AuNP)-based Drug Delivery and Molecular Imaging for Biomedical Applications”, Archives of Pharmacal Research 37, 53-59, 2014 http://dx.doi.org/10.1007/s12272-013-0273-5

19. Oh YJ., Cho IH., Lee H., Park KJ., Lee H.*, Park SY*. “Bio-inspired catechol chemistry: a new way to develop a re-moldable and injectable coacervate hydrogel”, Chem. Commun. 48, 11895-11897, 2012 http://dx.doi.org/10.1039/C2CC36843A

18. Lee H. et al “Molecularly Self-assembled Nucleic Acid Nanoparticles for Targeted In Vivo siRNA Delivery”, Nature Nanotechnology 7, 389-393, 2012 http://dx.doi.org/10.1038/nnano.2012.73

17. Lee K., Lee H., Lee. K.W., and Park T. G. “Optical imaging of intracellular reactive oxygen species for the assessment of the cytotoxicity of nanoparticles”, Biomaterials 32, 2556-2565, 2011. http://dx.doi.org/10.1016/j.biomaterials.2010.11.072

16. Byun E., Kim J., Kang S.M., Lee H., Bang D., and Lee H. “Surface PEGylation via Native Chemical Ligation”, Bioconjugate Chem. 22, 4-8, 2011. http://dx.doi.org/10.1021/bc100285p

15. Lee K., Lee H., Bae K.H. and Park T.G. “Heparin immobilized gold nanoparticles for targeted detection and apoptotic death of metastatic cancer cells”, Biomaterials 31, 6540- 6535, 2010. doi:10.1016/j.biomaterials.2010.04.046

14. Lee H., Park S.Y., and Lee H. “Catechol grafted Poly(ethylene Glycol) Copolymer for Material Independent surface PEGylation”, Langmuir 26, 3790-3793, 2010. http://dx.doi.org/10.1021/la904909h

13. Lee H., Kim I.K., and Park T.G. “Intracellular unpacking and trafficking of cell penetrating peptide conjugated siRNA/quantum dot complexes”, Bioconjug. Chem. 21, 289-295, 2010. http://dx.doi.org/10.1021/bc900342p

12. Kim T.G., Lee H., Jang Y., and Park T.G., “Controlled release of paclitaxel from heparinized metal stent fabricated by layer-by- layer assembly of polylysine and hyaluronic acid-g-poly(lactic-co- glycolic acid) micelles encapsulating paclitaxel”, Biomacromolecules 10, 1532-1539, 2009. http://dx.doi.org/10.1021/bm900116r

11. Lee H., Ahn C., and Park T.G. “Poly(lactic-co-glycolic acid) Grafted Hyaluronic Acid Copolymer Micelle Nanoparticles for Target-specific Delivery of Doxorubicin”, Macromolecular Biosci.9, 336-42, 2009. http://dx.doi.org/10.1002/mabi.200800229

10. Lee H., Lee K., Kim I.K., and Park T.G. “Fluorescent gold nanoprobe sensitive to intracellular reactive oxygen species”, Advanced Functional Materials 19, 1839-2012, 2009. http://dx.doi.org/10.1002/adfm.200801838

9. Lee H., Lee K., Kim I.K., and Park T.G. “Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes”, Biomaterials 29, 4709-18, 2008. doi:10.1016/j.biomaterials.2008.08.038

8. Lee H., Lee K., and Park T.G. “Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity”, Bioconjug. Chem. 19, 1319-25, 2008. http://dx.doi.org/10.1021/bc8000485

7. Lee H.and Park T.G. “Photo-crosslinkable, biomimetic, and thermo-sensitive pluronic grafted hyaluronic acid copolymers for injectable delivery of chondrocytes”, J. Biomed. Mater. Res. A 127, 22-32, 2008. http://dx.doi.org/10.1002/jbm.a.31983

6. Lee H., Jeong Y., and Park T.G. “Shell cross-linked hyaluronic acid/polylysine layer-by- layer polyelectrolyte microcapsules prepared by removal of reducible hyaluronic acid microgel cores”, Biomacromolecules 8, 3705-11. 2007. http://dx.doi.org/10.1021/bm700854j

5. Lee H., Mok H., Lee S., Oh Y., and Park T.G. “Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels”, J. Control Release 119, 245-52, 2007. doi:10.1016/j.jconrel.2007.02.011

4. Lee H., Chung H.J., and Park T.G. “Perspectives on: local and sustained delivery of angiogenic growth factors”, J. Bioactive and Compatible Polymers 22, 89-114, 2007. http://dx.doi.org/10.1177/0883911506073363

3. Yoon J.J., Chung H.J., Lee H., Park T.G. “Heparin Immobilized Biodegradable Scaffolds for Local and Sustained Release of Angiogenic Growth Factor”, J. Biomed. Mater. Res. A 79A, 934-942, 2006 http://dx.doi.org/10.1002/jbm.a.30843

2. Yang F., Williams C.G., Wang D.A., Lee H., Manson P.N., and Elisseeff J.H. “The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells”, Biomaterials 26, 5991-8, 2005. doi:10.1016/j.biomaterials.2005.03.018

1. Wang D.A., Williams C.G., Yang F., Cher N., Lee H., and Elisseeff J.H. “Bioresponsive phosphoester hydrogels for bone tissue engineering”, Tissue Eng. 11, 201-13, 2005. http://dx.doi.org/10.1089/ten.2005.11.201